Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036654 | 0.89 | ADORA1 (0.44) | ADORA1PTGDR2PDE3APDE5APDE4B | |
| SCHEMBL7035541 | 0.81 | ADORA1 (0.45) | ADORA1PTGDR2KDM4EPDE3APDE5A | |
| SCHEMBL7038368 | 0.80 | ADORA1 (0.48) | ADORA1PTGDR2KDM4EPDE3APDE5A | |
| SCHEMBL7036909 | 0.79 | ADORA1 (0.43) | ADORA1KDM4EPDE3APDE5APDE4B | |
| SCHEMBL7033867 | 0.77 | ADORA1 (0.47) | ADORA1PTGDR2KDM4EPDE3APDE5A | |
| SCHEMBL7039890 | 0.76 | PDE5A (0.42) | ADORA1PDE3APDE5APDE4BALDH1A1 | |
| SCHEMBL7032871 | 0.71 | PDE3A (0.65) | ADORA1PDE3APDE5APDE4BALDH1A1 | |
| SCHEMBL7033864 | 0.71 | ADORA1 (0.38) | ADORA1PDE3APDE5APDE4B | |
| SCHEMBL7032843 | 0.67 | PDE5A (0.40) | ADORA1PTGDR2PDE3APDE5APDE4B | |
| SCHEMBL8639797 | 0.67 | ADORA1 (0.72) | ADORA1PTGDR2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |