SCHEMBL7033940

SCHEMBL7033940

OC/C(F)=C/c1ccc(Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
PYGL P06737 11/20 0.44
NPFFR2 Q9Y5X5 2/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
IGF1R P08069 1/20 0.37
CHAT P28329 1/20 0.36
TRPA1 O75762 1/20 0.36
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7033943 1.00 ALDH1A1 (0.45) ALDH1A1PYGLNPFFR2KMT2ANPSR1
SCHEMBL7152890 0.83 ALDH1A1 (0.44) ALDH1A1PYGLNPFFR2KMT2ANPSR1
SCHEMBL7152887 0.83 ALDH1A1 (0.44) ALDH1A1PYGLNPFFR2KMT2ANPSR1
SCHEMBL1689623 0.78 TRPA1 (0.41) ALDH1A1TRPA1HSD17B10HTT
SCHEMBL1689625 0.78 TRPA1 (0.41) ALDH1A1TRPA1HSD17B10HTT
SCHEMBL1689621 0.78 TRPA1 (0.41) ALDH1A1TRPA1HSD17B10HTT
SCHEMBL29879654 0.76 FBP1 (0.47) ALDH1A1KMT2ANPSR1CHATPOLB
SCHEMBL7070877 0.72 ALDH1A1 (0.48) ALDH1A1PYGLNPFFR2KMT2ANPSR1
SCHEMBL6960044 0.72 ALDH1A1 (0.47) ALDH1A1HTT
SCHEMBL7070880 0.72 ALDH1A1 (0.48) ALDH1A1PYGLNPFFR2KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2003-12-04 US disclosed
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 2002-06-06 US disclosed
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP disclosed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO disclosed
EP-0553081-B1 PESTICIDES ROUSSEL UCLAF (FR) 1996-02-28 EP disclosed
US-5326755-A Contain cyclopropane ring ROUSSEL UCLAF 1994-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES CBR1, CBR3, CYP2E1 ALDH1A1 798/4885PYGL 1965/4885NPFFR2 516/4885
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides CBR3, CBR1, CYP2E1 ALDH1A1 925/4885PYGL 2283/4885NPFFR2 797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.