Sugi Predict

Sugi Predict / Compounds / SCHEMBL703413

SCHEMBL703413

SCHEMBL703413

CC(=CC(=O)c1ccc(C)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.57
▸ HTT P42858 4/20 0.57
▸ NPSR1 Q6W5P4 4/20 0.57
▸ LMNA P02545 4/20 0.57
▸ SMN1; SMN2 Q16637 4/20 0.57
▸ HPGD P15428 3/20 0.57
▸ PKM P14618 2/20 0.57
▸ ATM Q13315 2/20 0.57
▸ NLRP1 Q9C000 1/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ NTSR1 P30989 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ MAPT P10636 8/20 0.55
▸ THRB P10828 1/20 0.55
▸ NPC1 O15118 4/20 0.49
▸ RAB9A P51151 4/20 0.49
▸ POLB P06746 1/20 0.49
▸ CYP1B1 Q16678 1/20 0.49
▸ CES2 O00748 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14990811 1.00 ALDH1A1 (0.57) ALDH1A1HTTNPSR1LMNASMN1; SMN2
SCHEMBL2791186 0.83 NFE2L2 (0.59) ALDH1A1LMNASMN1; SMN2HPGDMEN1
SCHEMBL8104632 0.83 NFE2L2 (0.59) ALDH1A1LMNASMN1; SMN2HPGDMEN1
SCHEMBL11154858 0.82 ALDH1A1 (0.54) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL11713737 0.82 MAPT (0.59) ALDH1A1SMN1; SMN2HPGDTDP1MAPT
SCHEMBL11154856 0.82 ALDH1A1 (0.54) ALDH1A1HTTNPSR1LMNAHPGD
SCHEMBL20673437 0.82 ALDH1A1 (0.59) ALDH1A1HTTNPSR1LMNASMN1; SMN2
SCHEMBL8844390 0.81 ALDH1A1 (0.64) ALDH1A1HTTNPSR1LMNASMN1; SMN2
SCHEMBL11710569 0.81 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2HPGDMEN1KMT2A
SCHEMBL15784370 0.79 ALDH1A1 (0.61) ALDH1A1HTTNPSR1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883941-B2 Methods and apparatus for controlled single electron transfer living radical polymerization HENKEL CORPORATION (US) 2014-11-11 — — US claimed
US-7863396-B2 Silicon compounds CHISSO CORPORATION (JP) 2011-01-04 — — US claimed
US-20240076421-A1 POLYMERIZATION PHOTOINHIBITOR THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-03-07 — — US disclosed
US-11851511-B2 Polymerization photoinhibitor THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-12-26 — — US disclosed
US-20220106417-A1 POLYMERIZATION PHOTOINHIBITOR THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2022-04-07 — — US disclosed
US-11174326-B2 Polymerization photoinhibitor THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2021-11-16 — — US disclosed
US-20210161869-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2021-06-03 — — US disclosed
US-20210115167-A1 POLYMERIZATION PHOTOINHIBITOR THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2021-04-22 — — US disclosed
US-10966967-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2021-04-06 — — US disclosed
US-20200281905-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2020-09-10 — — US disclosed
US-10695328-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2020-06-30 — — US disclosed
US-20100216954-A1 Modified Thermoplastic Resin KANEKA CORPORATION (JP) 2010-08-26 — — US disclosed
US-20100105798-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-04-29 — — US disclosed
US-20090275702-A1 MOISTURE CURABLE POLYMER HAVING SiF GROUP, AND CURABLE COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 2009-11-05 — — US disclosed
US-7601781-B2 Curable compositions KANEKA CORPORATION (JP) 2009-10-13 — — US disclosed
US-20090247712-A1 CURABLE ORGANIC POLYMER AND METHOD FOR PRODUCTION THEREOF, AND CURABLE COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 2009-10-01 — — US disclosed
US-20090136774-A1 Resin Composition Comprising Olefinic Block polymer and Application Thereof MITSUI CHEMICALS, INC. (JP) 2009-05-28 — — US disclosed
US-20090025870-A1 CURABLE COMPOSITION AND SEALING METHOD THREE BOND CO., LTD. (JP) 2009-01-29 — — US disclosed
US-20080177001-A1 CURABLE COMPOSITIONS KANEKA CORPORATION (JP) 2008-07-24 — — US disclosed
US-20080097049-A1 Vinyl Polymers and Processes for Producing the Same KANEKA CORPORATION (JP) 2008-04-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210161869-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS DGAT2, MGAT2, MGAT1 ALDH1A1 284/4885HTT 2561/4885NPSR1 1606/4885
US-10966967-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors DGAT2, MGAT2, MGAT1 ALDH1A1 284/4885HTT 2561/4885NPSR1 1606/4885
US-10695328-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors DGAT2, MGAT2, MGAT1 ALDH1A1 284/4885HTT 2561/4885NPSR1 1606/4885
US-20200281905-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS DGAT2, MGAT2, MGAT1 ALDH1A1 284/4885HTT 2561/4885NPSR1 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.