Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028532 | 0.86 | KCNH2 (0.39) | KCNH2KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7034146 | 0.85 | CACNA1G (0.42) | KCNH2KDM4EALDH1A1L3MBTL1CACNA1G | |
| SCHEMBL7034144 | 0.85 | CACNA1G (0.42) | KCNH2KDM4EALDH1A1L3MBTL1CACNA1G | |
| SCHEMBL7033247 | 0.83 | KCNH2 (0.44) | KCNH2KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7034946 | 0.82 | KDM4E (0.44) | KCNH2KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL6739594 | 0.80 | KCNH2 (0.44) | KCNH2KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7032198 | 0.79 | KDM4E (0.45) | KCNH2KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7028528 | 0.78 | KMT2A (0.42) | KCNH2ALDH1A1KMT2APOLB | |
| SCHEMBL7028529 | 0.78 | KMT2A (0.42) | KCNH2ALDH1A1KMT2APOLB | |
| SCHEMBL7034824 | 0.76 | KCNH2 (0.39) | KCNH2KDM4EALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212095-A1 | New bispidine compounds and their use in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212095-A1 | New bispidine compounds and their use in the treatment of cardiac arrhythmias | KCNH1, LBR, CACNA1E | KCNH2 7/4885KDM4E 4058/4885ALDH1A1 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.