SCHEMBL7034261

SCHEMBL7034261

CC(C=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.49
GABBR1 Q9UBS5 2/20 0.49
CA2 P00918 3/20 0.48
CA1 P00915 2/20 0.48
ALDH1A1 P00352 5/20 0.47
CYP1A2 P05177 4/20 0.47
MAPT P10636 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TSHR P16473 3/20 0.47
CYP2D6 P10635 2/20 0.47
CYP3A4 P08684 2/20 0.47
BLM P54132 2/20 0.47
HIF1A Q16665 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
USP2 O75604 1/20 0.47
MAPK1 P28482 1/20 0.47
ATM Q13315 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30493643 0.80 ALDH1A1 (0.48) ALDH1A1CYP1A2MAPTTSHRNPSR1
SCHEMBL5486067 0.79 GABBR2 (0.47) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL1250152 0.77 CYP1A2 (0.62) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL284652 0.77 CA2 (0.58) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL15397235 0.77 GABBR2 (0.53) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL8650553 0.77 GABBR2 (0.45) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL185467 0.75 CA2 (0.56) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL8650154 0.75 GABBR2 (0.47) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL27898976 0.75 CYP3A4 (0.50) GABBR2GABBR1CA2CA1ALDH1A1
SCHEMBL8772288 0.74 CA2 (0.61) GABBR2GABBR1CA2CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369275-A PHOTOSTABILITY FOR POLYMERS CIBA-GEIGY AG (CH) 1983-01-18 US claimed
US-4293468-A Malonate derivatives as stabilizers for organic materials CIBA-GEIGY AG (CH) 1981-10-06 US claimed
JP-63014101-A None JP disclosed
EP-0733658-B1 Cycloolefin type random copolymer compositions and uses thereof MITSUI CHEMICALS INC (JP) 2003-03-19 EP disclosed
EP-0719824-B1 Low-dust granules of plastic additives CIBA SC HOLDING AG (CH) 2001-06-27 EP disclosed
EP-0652253-B1 Cycloolefin resin compositions MITSUI CHEMICALS INC (JP) 2000-05-03 EP disclosed
EP-0291208-B1 Cycloolefin type random copolymer compositions and uses thereof MITSUI PETROCHEMICAL IND (JP) 1997-08-06 EP disclosed
EP-0733658-A2 Cycloolefin type random copolymer compositions and uses thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-25 EP disclosed
EP-0652253-A2 Cycloolefin resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-05-10 EP disclosed
US-5395869-A Thermally stabilized thermoplastic cycloolefin in resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-03-07 US disclosed
EP-0423346-A1 CYCLOOLEFINIC RESIN COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-24 EP disclosed
US-4226999-A ANTIOXIDANTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1980-10-07 US disclosed
US-4202816-A ENOL-PIPERIDINE METAL COMPLEXES CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed
US-4197236-A Piperidine stabilizers CIBA-GEIGY CORPORATION (US) 1980-04-08 US disclosed
US-4185007-A Barbituric acid derivatives containing a phenolic moiety and/or a hindered amine moiety CIBA-GEIGY CORPORATION (US) 1980-01-22 US disclosed
US-4173599-A 2,2,6,6-Tetraalkyl-4-piperidyl ketones and ketals as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1979-11-06 US disclosed
US-4161592-A PHOTOSTABILIZERS AND ANTIOXIDANTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4151356-A STABILIZERS AGAINST OXIDATION AND LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-04-24 US disclosed
US-4148784-A HEAT, LIGHT AND OXIDATION RESISTANCE FOR SYNTHETIC POLYMERS CIBA-GEIGY CORPORATION (US) 1979-04-10 US disclosed
US-4144224-A FOR POLYOLEFINS, POLYAMIDES, AND POLYURETHANES CIBA-GEIGY CORPORATION (US) 1979-03-13 US disclosed