Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034658 | 1.00 | NAAA (0.45) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL13976822 | 0.91 | PPARA (0.45) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL2882888 | 0.90 | NAAA (0.40) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL3737218 | 0.89 | PPARA (0.44) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL7066044 | 0.89 | PPARA (0.44) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL4205621 | 0.89 | PPARA (0.44) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL4205626 | 0.89 | PPARA (0.44) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL5924646 | 0.88 | NAAA (0.48) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL5924643 | 0.88 | NAAA (0.48) | NAAAPPARAIL6STFAAHIDH1 | |
| SCHEMBL1049822 | 0.88 | NAAA (0.46) | NAAAPPARAIL6STFAAHIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800764-B2 | PREPARING CHIRALLY PURE S-ENANTIOMERS OF ALPHA -AMINO ACIDS COMPRISING THE STEPS OF: A) PREPARING AN ORGANOMETALLIC REAGENT FROM AN ALKYL HALIDE OF THE FORMULA (R) 2CH(CH2)NCH2X; B) ADDING THE ORGANOMETALLIC REAGENT TO CARBON DIOXIDE TO FORM | WYETH | 2004-10-05 | — | — | US | claimed |
| US-20030144531-A1 | Process for the synthesis of chirally pure beta-amino-alcohols | WYETH (US) | 2003-07-31 | — | — | US | claimed |
| US-20230089867-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | NOVARTIS AG (CH) | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144531-A1 | Process for the synthesis of chirally pure beta-amino-alcohols | ADH1C, ADH1A, ALDH7A1 | NAAA 2236/4885PPARA 1384/4885IL6ST 1591/4885 |
| US-20230089867-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | PCSK9, PCSK7, PCSK6 | NAAA 891/4885PPARA 2673/4885IL6ST 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.