Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035013 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL6438252 | 0.82 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL6438249 | 0.82 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL6438248 | 0.82 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL24376117 | 0.81 | HDAC1 (0.57) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL11527446 | 0.80 | HDAC1 (0.42) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL11527443 | 0.80 | HDAC1 (0.42) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| Hydrochloric Acid SCHEMBL2473896 | 0.79 | HDAC1 (0.55) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL24593486 | 0.78 | HDAC1 (0.41) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL7462866 | 0.78 | MTNR1A (0.50) | HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | ORMDL3, SGMS1, HEATR1 | HDAC1 752/4885HDAC2 951/4885HDAC3 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.