Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438248 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL6438249 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL7803886 | 0.82 | CES2 (0.50) | HDAC1HDAC2HDAC3NCOR2CES2 | |
| SCHEMBL7035013 | 0.82 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL7803887 | 0.82 | CES2 (0.50) | HDAC1HDAC2HDAC3NCOR2CES2 | |
| SCHEMBL7035015 | 0.82 | HDAC1 (0.44) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL15816134 | 0.81 | HDAC1 (0.57) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL5873456 | 0.81 | HDAC1 (0.57) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL5873458 | 0.81 | HDAC1 (0.57) | HDAC1HDAC2HDAC3NCOR2MAOA | |
| SCHEMBL11527446 | 0.80 | HDAC1 (0.42) | HDAC1HDAC2HDAC3NCOR2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | HDAC1 2806/4885HDAC2 1090/4885HDAC3 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.