Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034423 | 0.90 | P2RX7 (0.33) | HIF1AP2RX7TMEM97SIGMAR1F10 | |
| SCHEMBL6155148 | 0.77 | HIF1A (0.40) | HIF1AP2RX7F10NPC1MAPT | |
| SCHEMBL6155140 | 0.77 | HIF1A (0.40) | HIF1AP2RX7F10NPC1MAPT | |
| SCHEMBL7036504 | 0.75 | HIF1A (0.38) | HIF1ASMN1; SMN2 | |
| SCHEMBL7033758 | 0.71 | HIF1A (0.46) | HIF1AMAPTSMN1; SMN2 | |
| SCHEMBL7033763 | 0.71 | HIF1A (0.46) | HIF1AMAPTSMN1; SMN2 | |
| SCHEMBL7705191 | 0.70 | HIF1A (0.52) | HIF1AP2RX7F10MAPTSMN1; SMN2 | |
| SCHEMBL6156221 | 0.70 | HIF1A (0.52) | HIF1AP2RX7F10MAPTSMN1; SMN2 | |
| SCHEMBL9569041 | 0.69 | ALDH1A1 (0.39) | HIF1A | |
| SCHEMBL6156111 | 0.69 | SMN1; SMN2 (0.37) | HIF1AF10NPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |