Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155140 | 1.00 | HIF1A (0.40) | HIF1ASMN1; SMN2MAPTNPC1F10 | |
| SCHEMBL6156111 | 0.91 | SMN1; SMN2 (0.37) | HIF1ASMN1; SMN2MAPTNPC1F10 | |
| SCHEMBL6156939 | 0.83 | LMNA (0.36) | SMN1; SMN2MAPTLMNA | |
| SCHEMBL6156122 | 0.81 | LMNA (0.31) | SMN1; SMN2MAPTNPC1LMNARAB9A | |
| SCHEMBL7705191 | 0.78 | HIF1A (0.52) | HIF1ASMN1; SMN2MAPTF10P2RX7 | |
| SCHEMBL6156221 | 0.78 | HIF1A (0.52) | HIF1ASMN1; SMN2MAPTF10P2RX7 | |
| SCHEMBL7035279 | 0.77 | HIF1A (0.41) | HIF1ASMN1; SMN2MAPTNPC1F10 | |
| SCHEMBL7127230 | 0.77 | HIF1A (0.46) | HIF1ASMN1; SMN2MAPTNPC1F10 | |
| SCHEMBL6156510 | 0.73 | HIF1A (0.38) | HIF1ASMN1; SMN2ALDH1A1SLC6A3HPGD | |
| SCHEMBL6157925 | 0.72 | CNR1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-B1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |