Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038634 | 0.99 | ACLY (0.56) | ACLYRXFP1TRIM24TRIM33IGF2BP2 | |
| Lithium Ion SCHEMBL7035454 | 0.88 | RXFP1 (0.47) | ACLYRXFP1TRIM24TRIM33TRPM2 | |
| SCHEMBL7036226 | 0.87 | RXFP1 (0.47) | ACLYRXFP1TRIM24TRIM33IGF2BP2 | |
| SCHEMBL2272713 | 0.78 | ACLY (0.84) | ACLYRXFP1IGF2BP2ALDH1A1HDAC2 | |
| SCHEMBL2559790 | 0.76 | TRIM24 (0.60) | TRIM24TRIM33ALDH1A1MEN1KMT2A | |
| SCHEMBL1534369 | 0.76 | RXFP1 (0.68) | ACLYRXFP1ALDH1A1P2RX1MEN1 | |
| SCHEMBL418647 | 0.75 | SERPINE1 (0.66) | ACLYSERPINE1RAB9A | |
| SCHEMBL7038142 | 0.75 | IGF2BP2 (0.54) | ACLYIGF2BP2SERPINE1HDAC2PLK1 | |
| SCHEMBL7037046 | 0.75 | PPARG (0.62) | ACLYRXFP1TRIM24TRIM33PTPN1 | |
| SCHEMBL7038170 | 0.74 | SERPINE1 (0.53) | ACLYRXFP1SERPINE1ALDH1A1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | disclosed |
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073862-A1 | Compounds | PPARG, PPARA, PPARD | ACLY 451/4885RXFP1 258/4885TRIM24 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.