Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035753 | 1.00 | LMNA (0.52) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7036099 | 0.81 | LMNA (0.53) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7031426 | 0.81 | LMNA (0.53) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7036097 | 0.81 | LMNA (0.53) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7031428 | 0.81 | LMNA (0.53) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7038815 | 0.81 | LMNA (0.50) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7038814 | 0.81 | LMNA (0.50) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7029511 | 0.80 | LMNA (0.51) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7029506 | 0.80 | LMNA (0.51) | LMNAMAPTPOLBHPGDSSTR3 | |
| SCHEMBL7030757 | 0.79 | LMNA (0.55) | LMNAPOLBHPGDTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2003-12-04 | — | — | US | claimed |
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 2002-06-06 | — | — | US | claimed |
| EP-1003714-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-05-31 | — | — | EP | claimed |
| WO-1999001422-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1999-01-14 | — | — | WO | claimed |
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2003-12-04 | — | — | US | disclosed |
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 2002-06-06 | — | — | US | disclosed |
| EP-1003714-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999001422-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | CBR1, CBR3, CYP2E1 | LMNA 1663/4885MAPT 4759/4885POLB 3707/4885 |
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | CBR3, CBR1, CYP2E1 | LMNA 1581/4885MAPT 4727/4885POLB 3491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.