O-Xylene

O-Xylene

SCHEMBL7035837

Cc1ccccc1C.O=C1CCCCC1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.55
TRIM33 Q9UPN9 2/20 0.55
ALDH1A1 P00352 1/20 0.55
TSHR P16473 2/20 0.50
ACHE P22303 1/20 0.50
ALOX5 P09917 2/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2A6 P11509 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
MAPT P10636 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL18204052 0.98 TRIM24 (0.52) TRIM24TRIM33ALDH1A1TSHRACHE
O-Xylene SCHEMBL3142787 0.97 TSHR (0.53) TRIM24TRIM33ALDH1A1TSHRACHE
O-Xylene SCHEMBL28222227 0.91 TSHR (0.46) TRIM24TRIM33ALDH1A1TSHRACHE
Orthocresol SCHEMBL7088957 0.85 ALDH1A1 (0.44) TRIM24TRIM33ALDH1A1TSHRMEN1
Cyclopentanone SCHEMBL28203803 0.83 TRIM24 (0.48) TRIM24TRIM33ALDH1A1TSHRCYP2A6
Cycloheptanone SCHEMBL28118482 0.83 TRIM24 (0.52) TRIM24TRIM33ALDH1A1TSHRACHE
Toluene SCHEMBL27890798 0.83 TRIM24 (0.52) TRIM24TRIM33ALDH1A1TSHRACHE
Toluene SCHEMBL1635353 0.83 TRIM24 (0.52) TRIM24TRIM33ALDH1A1TSHRACHE
P-Xylene SCHEMBL28222223 0.81 TRIM24 (0.50) TRIM24TRIM33ALDH1A1TSHRACHE
Toluene SCHEMBL28202304 0.81 TRIM24 (0.50) TRIM24TRIM33ALDH1A1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1530208-A Wood refreshing and corrosion proofing process for moving ancient building 武义县工艺美术研究所 2004-09-22 CN claimed
CN-1010102-B Transparent colored paint for styrene copolymer type glass UNIV CHINESE OVERSEAS (CN) 1990-10-24 CN claimed
CN-108700809-A Colored resin composition, filter substrate and liquid crystal display device 东丽株式会社 2018-10-23 CN disclosed
CN-104140282-B A kind of method for manufacture of ceramic plate using glass fabric as reinforcing material 江西盛祥电子材料股份有限公司 2017-11-21 CN disclosed
CN-103664682-B A kind of method of synthesizing 2-methane amide pimelinketone CHINA UNIVERSITY OF MINING AND TECHNOLOGY (CN) 2016-01-20 CN disclosed
CN-104774523-A Novel corrosion-resistant nano composite paint and preparation method thereof CHEN XI 2015-07-15 CN disclosed
CN-104140282-A Method for manufacturing ceramic plate with glass fiber cloth as reinforcing material JIANGXI SHENGXIANG ELECTRONIC MATERIAL CO LTD 2014-11-12 CN disclosed
CN-102599199-B Microcapsule suspending agent as well as preparation method and application thereof UNIV SOUTH CHINA AGRICULT 2014-07-09 CN disclosed
CN-103664682-A Synthetic method for 2-formamide cyclohexanone UNIV CHINA MINING 2014-03-26 CN disclosed
CN-102239890-B Microcapsule suspension used for preventing and controlling spiraling whitefly and preparation method thereof UNIV SOUTH CHINA AGRICULT 2013-08-07 CN disclosed
CN-102599199-A Microcapsule suspending agent as well as preparation method and application thereof UNIV SOUTH CHINA AGRICULT 2012-07-25 CN disclosed
CN-1110606-C Method and structure for protecting primary cable system of suspension bridge BEIJING INST OF AVIAT MATERIAL (CN) 2003-06-04 CN disclosed
EP-0894840-B1 Organopolysiloxane composition for surface treatment and surface-treated EPDM articles GE TOSHIBA SILICONES CO LTD (JP) 2003-02-12 EP disclosed
CN-1068596-C Pesticidal tri-oximino heterocyclic compounds NOVARTIS AG (CH) 2001-07-18 CN disclosed
CN-2394952-Y Protective structure for main cable of suspension bridge BEIJING AVIAT MATERIAL I (CN) 2000-09-06 CN disclosed
CN-1263602-A Method of fabricating distributed reflection multilayer mirror SEIKO EPSON CORP (JP) 2000-08-16 CN disclosed
US-6057042-A COMPRISING THE REACTION PRODUCT OF A SILANE/SILOXANE WITH AN AMINOALKYL GROUP AND AN ALKOXY GROUP, A SILANE/SILOXANE HAVING AN EPOXY GROUP AND ALKOXY GROUP AND AN POLYSILOXANE WITH AMINO GROUP; PROVIDES NON-STICKY, WATER-REPELLENT FILM TOSHIBA SILICONE CO., LTD. (JP) 2000-05-02 US disclosed
CN-1245233-A Method and structure for protecting primary cable system of suspension bridge BEIJING GENERAL INST OF AVIAT (CN) 2000-02-23 CN disclosed
EP-0636135-A1 TRIAZOLE COMPOUNDS Japat Ltd (CH) 1995-02-01 EP disclosed
US-4407927-A ANTIHALATION AGENT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-10-04 US disclosed