Orthocresol

Orthocresol

SCHEMBL7088957

Cc1ccccc1O.O=C1CCCCC1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TRIM24 O15164 2/20 0.44
TRIM33 Q9UPN9 2/20 0.44
TRPA1 O75762 2/20 0.40
ATM Q13315 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
BCL2L1 Q07817 1/20 0.39
BAD Q92934 1/20 0.39
BRD4 O60885 1/20 0.39
ESR2 Q92731 2/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
KMT2A Q03164 1/20 0.38
DBH P09172 2/20 0.37
MMP2 P08253 1/20 0.37
CXCR2 P25025 1/20 0.37
KDM4E B2RXH2 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL7035837 0.85 TRIM24 (0.55) ALDH1A1TRIM24TRIM33MEN1KMT2A
Orthocresol SCHEMBL11055527 0.85 TRPA1 (0.52) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL23093519 0.85 TRPA1 (0.52) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL28051221 0.85 TRPA1 (0.52) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL9063647 0.85 TRPA1 (0.52) ALDH1A1TRPA1ATMCYP1A2CYP2C19
O-Xylene SCHEMBL18204052 0.83 TRIM24 (0.52) ALDH1A1TRIM24TRIM33MEN1KMT2A
O-Xylene SCHEMBL3142787 0.83 TSHR (0.53) ALDH1A1TRIM24TRIM33MEN1KMT2A
Orthocresol SCHEMBL8995948 0.80
Orthocresol SCHEMBL10419161 0.78 TRPA1 (0.60) ALDH1A1TRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL170162 0.78 TRPA1 (0.60) ALDH1A1TRPA1ATMCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333075-A1 COATING COMPOSITION AND METHOD OF CAN INSIDE COATING KANSAI PAINT CO., LTD. (JP) 2003-08-06 EP disclosed