O-Xylene

O-Xylene

SCHEMBL3142787

Cc1ccccc1C.O=C1CCCC1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
TRIM24 O15164 2/20 0.53
TRIM33 Q9UPN9 2/20 0.53
ACHE P22303 1/20 0.53
ALDH1A1 P00352 2/20 0.50
ALOX5 P09917 2/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP2C9 P11712 1/20 0.38
MAPT P10636 1/20 0.38
DDB1 Q16531 2/20 0.37
CRBN Q96SW2 2/20 0.37
HDAC4 P56524 1/20 0.37
MGLL Q99685 1/20 0.37
PARP1 P09874 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL7035837 0.97 TRIM24 (0.55) TSHRTRIM24TRIM33ACHEALDH1A1
O-Xylene SCHEMBL18204052 0.95 TRIM24 (0.52) TSHRTRIM24TRIM33ACHEALDH1A1
O-Xylene SCHEMBL28222227 0.89 TSHR (0.46) TSHRTRIM24TRIM33ACHEALDH1A1
Cyclopentanone SCHEMBL28203803 0.85 TRIM24 (0.48) TSHRTRIM24TRIM33ALDH1A1PARP1
Orthocresol SCHEMBL7088957 0.83 ALDH1A1 (0.44) TSHRTRIM24TRIM33ALDH1A1MEN1
Toluene SCHEMBL10011124 0.82 LMNA (0.55) TSHRTRIM24TRIM33ACHEALDH1A1
Toluene SCHEMBL1635353 0.80 TRIM24 (0.52) TSHRTRIM24TRIM33ACHEALDH1A1
Cycloheptanone SCHEMBL28118482 0.80 TRIM24 (0.52) TSHRTRIM24TRIM33ACHEALDH1A1
Toluene SCHEMBL27890798 0.80 TRIM24 (0.52) TSHRTRIM24TRIM33ACHEALDH1A1
P-Xylene SCHEMBL28222223 0.78 TRIM24 (0.50) TSHRTRIM24TRIM33ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291005-A Polyamide-imide resin composition and fluoro coatings 日立化成株式会社 2018-07-17 CN disclosed
US-20100000769-A1 COMPOSITE MAGNETIC BODY, METHOD OF MANUFACTURING THE SAME, CIRCUIT BOARD USING THE SAME, AND ELECTRONIC APPARATUS USING THE SAME NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) 2010-01-07 US disclosed
EP-2117018-A1 COMPOSITE MAGNETIC BODY, ITS MANUFACTURING METHOD, CIRCUIT SUBSTRATE USING THE SAME, AND ELECTRONIC DEVICE USING THE SAME National University Corporation Tohoku University (JP) 2009-11-11 EP disclosed