Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568616 | 0.68 | MAPT (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1386080 | 0.64 | GAA (0.57) | ALDH1A1 | |
| SCHEMBL5688979 | 0.64 | GAA (0.57) | ALDH1A1 | |
| SCHEMBL5688782 | 0.64 | GAA (0.57) | ALDH1A1 | |
| SCHEMBL5567729 | 0.64 | KDM4E (0.36) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL7313114 | 0.63 | GAA (0.56) | ALDH1A1TSHR | |
| SCHEMBL7318714 | 0.63 | AHR (0.38) | — | |
| SCHEMBL7321145 | 0.63 | MAPT (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7307891 | 0.62 | MAPT (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7323833 | 0.62 | AHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964852-B1 | INDOLECARBOXYLIC COMPOUNDS AND THEIR USE AS PHARMACEUTICAL COMPOUNDS | OREAL (FR) | 2003-03-12 | — | — | EP | claimed |