Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 19/20 | 0.80 |
| ▸ | MTTP | P55157 | 18/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038349 | 1.00 | APOB (0.80) | APOBMTTP | |
| SCHEMBL7039821 | 0.86 | MTTP (0.75) | APOBMTTP | |
| SCHEMBL13591636 | 0.83 | MTTP (0.84) | APOBMTTP | |
| SCHEMBL13591653 | 0.81 | APOB (0.88) | APOBMTTP | |
| SCHEMBL7039826 | 0.81 | MTTP (1.00) | APOBMTTP | |
| SCHEMBL13591631 | 0.79 | APOB (0.71) | APOBMTTP | |
| SCHEMBL10265197 | 0.78 | APOB (1.00) | APOBMTTP | |
| SCHEMBL13591630 | 0.78 | APOB (0.79) | APOBMTTP | |
| SCHEMBL7764352 | 0.74 | APOB (1.00) | APOBMTTP | |
| SCHEMBL7764346 | 0.74 | APOB (1.00) | APOBMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162788-A1 | Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-08-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162788-A1 | Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals | APOB, LIPC, MTPN | APOB 1/4885MTTP 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.