Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394938 | 0.84 | EPHX2 (0.54) | EPHX2KCNH2MAPT | |
| SCHEMBL29195193 | 0.84 | ALDH1A1 (0.40) | SIGMAR1CNR1CNR2MAPTL3MBTL1 | |
| SCHEMBL12194495 | 0.82 | EPHX2 (0.54) | EPHX2KCNH2MAPT | |
| SCHEMBL30889345 | 0.82 | EPHX2 (0.57) | EPHX2KCNH2MAPT | |
| SCHEMBL8921829 | 0.82 | EPHX2 (0.57) | EPHX2KCNH2MAPT | |
| SCHEMBL10878735 | 0.82 | EPHX2 (0.57) | EPHX2KCNH2MAPT | |
| SCHEMBL16753020 | 0.82 | EPHX2 (0.57) | EPHX2KCNH2MAPT | |
| SCHEMBL3924849 | 0.82 | EPHX2 (0.57) | EPHX2KCNH2MAPT | |
| SCHEMBL20163176 | 0.82 | CALM1 (0.58) | CALM1CTSL | |
| SCHEMBL27968343 | 0.80 | TP53 (0.48) | MAPTCALM1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A4 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO (JP) | 2003-02-26 | — | — | EP | disclosed |
| CN-1367784-A | Process for preparing substituted propenone derivatives | SHIONOGI & CO (JP) | 2002-09-04 | — | — | CN | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000075122-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2000-12-14 | — | — | WO | disclosed |