Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.58 |
| ▸ | CTRC | Q99895 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680764 | 0.89 | CYP2A6 (0.53) | CALM1CTRCCTSLIDH1SMN1; SMN2 | |
| SCHEMBL27968343 | 0.89 | TP53 (0.48) | CALM1CTRCCTSLIDH1NPC1 | |
| SCHEMBL9338807 | 0.89 | TDP1 (0.50) | CALM1CTRCCTSLIDH1NPC1 | |
| Hydrochloric Acid SCHEMBL1169925 | 0.87 | CYP2A6 (0.52) | CALM1CTRCCTSLIDH1HPGD | |
| SCHEMBL18294977 | 0.84 | CALM1 (0.46) | CALM1CTRCCTSLIDH1NPC1 | |
| SCHEMBL4155853 | 0.84 | CTSL (0.46) | CALM1CTSLIDH1NPC1HPGD | |
| SCHEMBL3180066 | 0.84 | CHRM2 (0.47) | CALM1CTSLNPC1RAB9A | |
| SCHEMBL10910046 | 0.84 | CALM1 (0.46) | CALM1CTRCCTSLIDH1NPC1 | |
| Water SCHEMBL9667780 | 0.82 | CHRM2 (0.45) | CALM1CTSLNPC1RAB9A | |
| SCHEMBL7035982 | 0.82 | EPHX2 (0.48) | CALM1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | claimed |
| EP-4359382-A1 | TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS | Chevron Phillips Chemical Company LP (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117881658-A | Two-step synthesis of pyrrole compounds from furan compounds | 切弗朗菲利浦化学公司 | 2024-04-12 | — | — | CN | disclosed |
| US-11608317-B2 | Two-step synthesis of pyrrole compounds from furan compounds | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2023-03-21 | — | — | US | disclosed |
| WO-2022197944-A1 | TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2022-09-22 | — | — | WO | disclosed |
| US-20220298109-A1 | TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2022-09-22 | — | — | US | disclosed |
| US-10561594-B2 | Agent for stabilizing keratin fibers with 5-ring heterocycles | HENKEL AG & CO. KGAA (DE) | 2020-02-18 | — | — | US | disclosed |
| US-10561594-B2 | Agent for stabilizing keratin fibers with 5-ring heterocycles | HENKEL AG & CO. KGAA (DE) | 2020-02-18 | — | — | US | disclosed |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11608317-B2 | Two-step synthesis of pyrrole compounds from furan compounds | DDC, DHPS, ACMSD | CALM1 2695/4885CTRC 3353/4885CTSL 4342/4885 |
| US-20180140525-A1 | AGENT FOR STABILIZING KERATIN FIBERS WITH 5-RING HETEROCYCLES | KRT18, NDUFS5, NDUFA5 | CALM1 2016/4885CTRC 4836/4885CTSL 4759/4885 |
| US-10561594-B2 | Agent for stabilizing keratin fibers with 5-ring heterocycles | KRT18, NDUFS5, NDUFA5 | CALM1 2016/4885CTRC 4836/4885CTSL 4759/4885 |
| US-20220298109-A1 | TWO-STEP SYNTHESIS OF PYRROLE COMPOUNDS FROM FURAN COMPOUNDS | DDC, DHPS, ACMSD | CALM1 2695/4885CTRC 3353/4885CTSL 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.