Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036250 | 0.94 | ALOX15 (0.32) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL1268762 | 0.78 | SLC22A6 (0.39) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL29124667 | 0.77 | SLC22A6 (0.40) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL29115657 | 0.77 | SLC22A6 (0.40) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| Ammonia Solution, Strong SCHEMBL9958331 | 0.76 | TDP1 (0.42) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL4683182 | 0.76 | ALOX15 (0.57) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL10309227 | 0.76 | ALOX15 (0.57) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL27637701 | 0.76 | GABRP (0.37) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL19293651 | 0.74 | ALOX15 (0.36) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 | |
| SCHEMBL18526466 | 0.74 | LMNA (0.54) | ALOX15SLC22A6CACNA2D1SMN1; SMN2CACNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659421-B1 | 2-Phenyl-3-aroylbenzothiophenes for treating menstrual symptoms | LILLY CO ELI (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-0659421-A1 | 2-Phenyl-3-azoylbenzothiophenes for treating menstrual symptoms | ELI LILLY AND COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |