Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971156 | 0.94 | ZDHHC7 (0.52) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL16860589 | 0.92 | ZDHHC7 (0.55) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL14155778 | 0.92 | ZDHHC7 (0.55) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL1415326 | 0.89 | ZDHHC7 (0.59) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL1021505 | 0.89 | ZDHHC7 (0.53) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL1415641 | 0.89 | ZDHHC7 (0.53) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL9620497 | 0.87 | ZDHHC7 (0.62) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL698352 | 0.87 | ALDH1A1 (0.44) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL729131 | 0.85 | ZDHHC7 (0.60) | ZDHHC7ALDH1A1TRPA1LCKPPARD | |
| SCHEMBL7353073 | 0.85 | ZDHHC7 (0.60) | ZDHHC7ALDH1A1TRPA1LCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186112-A | Universal fluorescent probe for selectively and sensitively detecting carbonyl halide | 遵义医科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-100404516-C | Process for preparing hexahydro pyridazine tricarboxylate | DALIAN LVYUAN PHARMACY CO LTD (CN) | 2008-07-23 | — | — | CN | disclosed |
| CN-1240710-C | Process for preparing bicyclic compounds and use of the process for preparing ICE inhibitor compounds | AIWENTIS PHARMACEUTIC OY (FR) | 2006-02-08 | — | — | CN | disclosed |
| CN-1654458-A | Process for preparing hexahydro pyridazine tricarboxylate | DALIAN LUYUAN PHARMACY CO LTD (CN) | 2005-08-17 | — | — | CN | disclosed |
| CN-1167711-C | Octahydro-6,10-dioxo-6h-pyridazino/1,2-a//1,2/diazepin-1-carboxylic acid derivatives, prepn. method and use for preparing therapeutically active compounds | ���˹��ء���³�� | 2004-09-22 | — | — | CN | disclosed |
| US-20030130269-A1 | Derivatives of octahydro-6, 10-dioxo-6H-pyridazino [1,2-a] [1,2] diazepine-1-carboxylic acid, their preparation process and their use in the preparation of therapeutically active compounds | AVENTIS PHARMA S.A. | 2003-07-10 | — | — | US | disclosed |
| US-6570012-B2 | Derivatives of octahydro-6, 10-dioxo-6H-pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, useful for preperation of therapeutically active compounds | AVENTIS PHARMA S.A. (FR) | 2003-05-27 | — | — | US | disclosed |
| US-6548664-B1 | Alkylation, hydrogenation, cyclization, condensation, deracemization | AVENTIS PHARMA S.A. (FR) | 2003-04-15 | — | — | US | disclosed |
| US-6512111-B1 | A method for preparing compounds of formula (I) ) wherein cyclization is carried out in a basic medium and in the presence of a phosphonic acid derivative and the use of said method as an intermediate step for preparing a compound | AVENTIS PHARMA S.A. (FR) | 2003-01-28 | — | — | US | disclosed |
| US-20020128473-A1 | Derivatives of octahydro-6,10-dioxo-6H-pyridazino [1,2-a] [1,2] diazepine-1-carboxylic acid, their preparation process and their use in the preparation of therapeutically active compounds | AVENTIS PHARMA S.A. | 2002-09-12 | — | — | US | disclosed |
| CN-1343218-A | Method for preparing bicyclic compounds and use of said method for preparing inhibitor compound | AIWENTIS PHARMACEUTIC OY (FR) | 2002-04-03 | — | — | CN | disclosed |
| WO-2001056997-A1 | PROCESS FOR PREPARING PIPERAZIC ACID DERIVATIVES THEREOF | LONZA AG (CH) | 2001-08-09 | — | — | WO | disclosed |
| CN-1306539-A | Octahydro-6,10-dioxo-6h-pyridazino/1,2-a//1,2/diazepin-1-carboxylic acid derivatives, prepn. method and use for preparing therapeutically active compounds | HOECHST MARION ROUSSEL INC (FR) | 2001-08-01 | — | — | CN | disclosed |
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0309624-B1 | COMPOSITION FOR ENHANCING PERCUTANEOUS ADMINISTRATION OF MEDICINE | NITTO DENKO CORPORATION (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5059628-A | Proline or prolinol ester to enhance absorption | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0309624-A1 | Composition for enhancing percutaneous administration of medicine | NITTO DENKO CORPORATION (JP) | 1989-04-05 | — | — | EP | disclosed |
| US-4234744-A | Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides | DEUTSCHE GOLD- UND SILBER SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130269-A1 | Derivatives of octahydro-6, 10-dioxo-6H-pyridazino [1,2-a] [1,2] diazepine-1-carboxylic acid, their preparation process and their use in the preparation of therapeutically active compounds | CYP2S1, DEGS1, GRIK1 | ZDHHC7 1542/4885ALDH1A1 575/4885TRPA1 2907/4885 |
| US-20020128473-A1 | Derivatives of octahydro-6,10-dioxo-6H-pyridazino [1,2-a] [1,2] diazepine-1-carboxylic acid, their preparation process and their use in the preparation of therapeutically active compounds | CYP2D6, THPO, CYP2B6 | ZDHHC7 778/4885ALDH1A1 16/4885TRPA1 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.