Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 3/20 | 0.42 |
| ▸ | NPY2R | P49146 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036644 | 0.81 | LSS (0.45) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL2797073 | 0.81 | STS (0.57) | RAB9ANPC1MAPTHTTSTS | |
| Hydrochloric Acid SCHEMBL7036137 | 0.81 | LSS (0.44) | RAB9ANPC1MAPTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL7040587 | 0.78 | LSS (0.52) | ALDH1A1POLB | |
| SCHEMBL7037885 | 0.76 | SMN1; SMN2 (0.55) | RAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL4773741 | 0.74 | MAPT (0.54) | MAPTSTS | |
| SCHEMBL10458902 | 0.74 | GAA (0.72) | RAB9ANPC1SMN1; SMN2LIPEGAA | |
| SCHEMBL7010527 | 0.74 | STS (0.49) | RAB9ANPC1MAPTHTTSMN1; SMN2 | |
| SCHEMBL4768561 | 0.73 | GPR119 (0.54) | RAB9ANPC1MAPTHTTSMN1; SMN2 | |
| SCHEMBL22324946 | 0.72 | ALDH1A1 (0.64) | MAPTHTTSTSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060162-B1 | URETHANES DERIVED FROM AZACYCLOALKANES, THIO AND DITHIO ANALOGUES, PRODUCTION AND USE THEREOF AS 2,3 EPOXYSQUALENE LANESTEROL CYCLASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-03-19 | — | — | EP | claimed |
| US-6339096-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERLIPIDAEMIAS, HYPERCHOLESTEROLAEMIAS AND ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-15 | — | — | US | claimed |
| US-6339096-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERLIPIDAEMIAS, HYPERCHOLESTEROLAEMIAS AND ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-15 | — | — | US | disclosed |