Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516554 | 0.87 | POLB (0.37) | ALDH1A1CHRM1TSHRCHRM2CHRM4 | |
| SCHEMBL2332385 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL9419509 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL29229107 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL5613336 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL2784663 | 0.81 | TSHR (0.38) | ALDH1A1CHRM1TSHRCHRM2CHRM4 | |
| SCHEMBL28800333 | 0.81 | HCAR2 (0.39) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL2321956 | 0.80 | — | — | |
| SCHEMBL6062638 | 0.80 | HCAR2 (0.41) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL204763 | 0.80 | POLB (0.44) | ALDH1A1LMNACHRM1ESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030027938-A1 | Synthesis of energetic polyester thermoplastic homopolymers and energetic thermoplastic elastomers formed therefrom | DEPARTMENT OF NATIONAL DEFENCE (CA) | 2003-02-06 | — | — | US | disclosed |
| EP-1229009-A1 | Synthesis of energetic polyester thermoplastic homopolymers and energetic thermoplastic elastomers formed therefrom | Department of National Defence (CA) | 2002-08-07 | — | — | EP | disclosed |
| US-20020103307-A1 | SYNTHESIS OF ENERGETIC POLYESTER THERMOPLASTIC HOMOPOLYMERS AND ENERGETIC THERMOPLASTIC ELASTOMERS FORMED THEREFROM | NATIONAL DEFENCE, DEPARTMENT OF (CA) | 2002-08-01 | — | — | US | disclosed |
| US-6417290-B1 | POLY(A-AZIDOMETHYL-A-METHYL-B-PROPIOLACTONE); PROPELLANTS, EXPLOSIVES | DEPARTMENT OF NATIONAL DEFENCE (CA) | 2002-07-09 | — | — | US | disclosed |