Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209069 | 0.73 | MASP2 (0.32) | — | |
| SCHEMBL9424713 | 0.70 | — | — | |
| SCHEMBL2293472 | 0.69 | SCN2A (0.55) | — | |
| SCHEMBL7255232 | 0.69 | AOC3 (0.34) | ALDH1A1 | |
| SCHEMBL7537360 | 0.67 | ERN1 (0.33) | ALDH1A1 | |
| SCHEMBL4439049 | 0.67 | HPGDS (0.50) | — | |
| SCHEMBL2488026 | 0.66 | P2RX7 (0.32) | CYP2A6ALDH1A1 | |
| SCHEMBL7819462 | 0.65 | CYP19A1 (0.39) | CYP2A6ALDH1A1 | |
| SCHEMBL15332010 | 0.63 | SCN2A (0.65) | ALDH1A1 | |
| SCHEMBL4028445 | 0.62 | NPSR1 (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400226-A1 | DERIVATIVES OF PYRROLOIMIDAZOLE OR ANALOGUES THEREOF WHICH ARE USEFUL FOR THE TREATMENT OF INTER ALIA CANCER | Emcure Pharmaceuticals Limited (IN) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017134555-A1 | DERIVATIVES OF PYRROLOIMIDAZOLE OR ANALOGUES THEREOF WHICH ARE USEFUL FOR THE TREATMENT OF INTER ALIA CANCER | EMCURE PHARMACEUTICALS LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003006012-A1 | COMPOUNDS AND METHODS FOR THE INHIBITION OF TRYPANOSOMA CRUZ I | YALE UNIVERSITY (US) | 2003-01-23 | — | — | WO | disclosed |