SCHEMBL7036740

SCHEMBL7036740

CC(C)(c1cccc(OCCCS(=O)(=O)O)c1)c1cccc(OCCCS(=O)(=O)O)c1.[NaH].[NaH]

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
POLB P06746 2/20 0.42
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 7/20 0.40
ALDH1A1 P00352 5/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.39
FFAR1 O14842 1/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PKM P14618 1/20 0.38
CACNA1B Q00975 2/20 0.38
MAPT P10636 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11336650 0.83 KDM4E (0.44) LMNAPOLBHTTKDM4EALDH1A1
SCHEMBL7601131 0.82 S1PR1 (0.49) LMNAPOLBHTTKDM4EALDH1A1
SCHEMBL10574067 0.79 SMN1; SMN2 (0.52) LMNAPOLBL3MBTL1KDM4EALDH1A1
SCHEMBL10572340 0.77 KDM4E (0.55) LMNAHTTKDM4EKMT2ASMN1; SMN2
SCHEMBL11277221 0.77 ESR1 (0.46) LMNAPOLBHTTKDM4EALDH1A1
SCHEMBL29412242 0.77 ALDH1A1 (0.52) LMNAPOLBHTTL3MBTL1KDM4E
SCHEMBL99458 0.77 ALDH1A1 (0.52) LMNAPOLBHTTL3MBTL1KDM4E
SCHEMBL13165261 0.77 L3MBTL1 (0.53) LMNAPOLBHTTL3MBTL1ALDH1A1
SCHEMBL11278627 0.76 KCNA3 (0.56) LMNAPOLBHTTL3MBTL1KDM4E
SCHEMBL29495043 0.76 TSHR (0.55) LMNAPOLBHTTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653484-B2 Triazine, benzotriazole, or benzophenone-type stabilizers conjugated to polyoxyalkylene groups; use as ultraviolet radiation absorbers in photographic materials CIBA SPECIALTY CHEMICALS CORPORATION 2003-11-25 US disclosed
EP-0912531-B1 POLYOXYALKYLENE SUBSTITUTED AND BRIDGED BENZOPHENONE DERIVATIVES AS UV ABSORBERS CIBA SC HOLDING AG (CH) 2003-03-19 EP disclosed
US-20020094320-A1 Polyoxyalkylene substituted and bridged benzotriazole derivatives TOAN VIEN VAN (CH) 2002-07-18 US disclosed
US-6369267-B1 RADIATION RESISTANCE TO ULTRAVIOLET RADIATION CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-09 US disclosed
EP-0912531-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 1999-05-06 EP disclosed
WO-1998003489-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-01-29 WO disclosed
EP-0295205-A1 Process for pad dyeing or finishing with continuous fixation of textile materials CIBA-GEIGY AG (CH) 1988-12-14 EP disclosed
US-4453946-A Dyeing assistant and use thereof in dyeing synthetic fibre material CIBA-GEIGY CORPORATION (US) 1984-06-12 US disclosed
US-4252534-A ALKYLBENZENE OR TETRALIN, ANIONIC SURFACTANT, NONIONIC WATER IMMISCIBLE SOLVENT CIBA-GEIGY CORPORATION (US) 1981-02-24 US disclosed
US-4207184-A DECOLORING BY ABSORPTION WITH SOLVATED POLYMER GEL CIBA-GEIGY AG (CH) 1980-06-10 US disclosed
US-4137042-A FLUORESCENT BRIGHTENERS, INDICATOR DYES CIBA-GEIGY AG (CH) 1979-01-30 US disclosed
US-4057388-A Dry heat process for dyeing and printing organic material which can be dyed with cationic dyestuffs CIBA-GEIGY AG (CH) 1977-11-08 US disclosed
US-4056352-A Dry transfer of organic compounds to webs CIBA-GEIGY AG (DT) 1977-11-01 US disclosed
US-4050269-A Dry thermal transfer of organic compounds by needle-bearing support CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-4042545-A Novel printing inks for sublimation transfer printing CIBA-GEIGY AG (CH) 1977-08-16 US disclosed
US-4040779-A Dry heat process to dyeing and printing organic material which can be dyed with cationic dyes CIBA-GEIGY AG (CH) 1977-08-09 US disclosed
US-3995992-A Transfer printing process for dyeing and printing organic material which can be dyed with cationic dyes CIBA-GEIGY AG (CH) 1976-12-07 US disclosed
US-3986823-A ONTO A WEB OF ORGANIC MATERIAL CIBA-GEIGY AG (CH) 1976-10-19 US disclosed
US-3966405-A N-Alkyl nitro phenyl diethylene triamine dyeing of acid modified synthetic fibers HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3963436-A Bis nitrophenyl diethylene triamine dyeing of synthetic acid modified fibers HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094320-A1 Polyoxyalkylene substituted and bridged benzotriazole derivatives TPT1, TYR, TERB1 LMNA 2729/4885POLB 1216/4885HTT 420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.