Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168750 | 0.88 | HTR2A (0.40) | CALM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9631883 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2CALM1KDM4EHTR2A | |
| SCHEMBL10791795 | 0.84 | CALM1 (0.46) | CALM1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7219053 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2MEN1KMT2AAKR1B1 | |
| SCHEMBL10776496 | 0.80 | IDH1 (0.40) | GABRA1GABRB2CALM1ALDH1A1HTR2A | |
| SCHEMBL11877132 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2MEN1KMT2AAKR1B1 | |
| SCHEMBL10599247 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2CALM1MEN1KMT2A | |
| SCHEMBL28379576 | 0.78 | ALDH1A1 (0.38) | CALM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16334907 | 0.77 | TP53 (0.38) | CALM1ALDH1A1HTR2A | |
| SCHEMBL25423951 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6779215-B2 | Power toothbrush | MCNEIL-PPC, INC. | 2004-08-24 | — | — | US | disclosed |
| US-20030182745-A1 | Power toothbrush | JOHNSON & JOHNSON CONSUMER INC. | 2003-10-02 | — | — | US | disclosed |
| EP-1348400-A1 | Power toothbrush | McNEIL-PPC, INC. (US) | 2003-10-01 | — | — | EP | disclosed |