Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219057 | 0.86 | ALDH1A1 (0.44) | CYP3A4CYP2C9ALDH1A1TSHRMEN1 | |
| SCHEMBL29720911 | 0.84 | CYP3A4 (0.59) | CYP3A4CYP2C9CES2CES1AKR1B1 | |
| SCHEMBL2850505 | 0.81 | ALDH1A1 (0.39) | CYP3A4CYP2C9ALDH1A1TSHRMEN1 | |
| SCHEMBL2850504 | 0.81 | ALDH1A1 (0.39) | CYP3A4CYP2C9ALDH1A1TSHRMEN1 | |
| SCHEMBL28957732 | 0.79 | CYP3A4 (0.53) | CYP3A4CYP2C9CES2CES1AKR1B1 | |
| SCHEMBL1791466 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2C9CES2CES1AKR1B1 | |
| SCHEMBL29859737 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2C9CES2CES1AKR1B1 | |
| SCHEMBL28379575 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2C9CES2CES1AKR1B1 | |
| SCHEMBL29120644 | 0.74 | CYP3A4 (0.58) | CYP3A4CYP2C9CES2CES1AKR1B1 | |
| SCHEMBL433428 | 0.74 | ALDH1A1 (0.44) | CYP3A4CYP2C9ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6779215-B2 | Power toothbrush | MCNEIL-PPC, INC. | 2004-08-24 | — | — | US | disclosed |
| US-20030182745-A1 | Power toothbrush | JOHNSON & JOHNSON CONSUMER INC. | 2003-10-02 | — | — | US | disclosed |
| EP-1348400-A1 | Power toothbrush | McNEIL-PPC, INC. (US) | 2003-10-01 | — | — | EP | disclosed |