Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850505 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL7219057 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL216869 | 0.83 | TSHR (0.43) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL7036787 | 0.81 | CYP3A4 (0.49) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL433428 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL3839387 | 0.77 | LMNA (0.47) | ALDH1A1TSHRAKR1C3ESR1MEN1 | |
| SCHEMBL28472907 | 0.75 | TRPA1 (0.52) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL9179184 | 0.75 | MME (0.42) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL7696952 | 0.73 | FBP1 (0.41) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL4911765 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723550-B2 | Process for preparing organic compounds | NOVARTIS AG (CH) | 2010-05-25 | — | — | US | disclosed |
| EP-1943205-B1 | PROCESS FOR PREPARING OF 2-ALKYL-3-ARYL-PROP-2 ENE-1-OLS | NOVARTIS AG (CH) | 2010-01-20 | — | — | EP | disclosed |
| US-20090105503-A1 | Process for Preparing organic compounds | NOVARTIS PHARMA AG (CH) | 2009-04-23 | — | — | US | disclosed |
| EP-1943205-A1 | PROCESS FOR PREPARING OF 2-ALKYL 3-ARYL PROP-2-2ENE-1-OLS | Speedel Experimenta AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2008055939-A2 | PROCESS FOR PREPARING 2-ALKYL-3-HETEROCYCLYL- PROP-2-EN- 1-OL DERIVATIVES | NOVARTIS AG (CH) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008055941-A1 | PROCESS FOR PREPARING OF 2-ALKYL-3-ARYL-PROP-2 ENE-1-OLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105503-A1 | Process for Preparing organic compounds | C1S, C9, C5 | ALDH1A1 1478/4885TSHR 324/4885AKR1C3 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.