Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | CNR1 | P21554 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033084 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HSD11B1CNR2CNR1 | |
| SCHEMBL7026797 | 0.83 | CA12 (0.48) | ALDH1A1TSHRSMN1; SMN2PSIP1KMT2A | |
| SCHEMBL7030066 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HSD11B1TSHRSMN1; SMN2RORC | |
| SCHEMBL55285 | 0.80 | CA1 (0.44) | ALDH1A1CYP3A4HSD11B1TSHRSMN1; SMN2 | |
| SCHEMBL5945169 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HSD11B1CNR2CNR1 | |
| SCHEMBL30302484 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD11B1CNR2CNR1 | |
| SCHEMBL6854169 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD11B1CNR2CNR1 | |
| SCHEMBL8773481 | 0.77 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD11B1CNR2CNR1 | |
| SCHEMBL11526370 | 0.77 | RAB9A (0.53) | ALDH1A1CYP3A4CNR2CNR1TSHR | |
| SCHEMBL6571778 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HSD11B1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841323-B1 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5902905-A | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0841323-A2 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |