SCHEMBL6571778

SCHEMBL6571778

CCN(CC)c1cccc(S(=O)(=O)[O-])c1.[Na+]

nearest known ligand 0.49

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 2/20 0.41
PPARG known ✓ P37231 1/20 0.40
CA12 known ✓ O43570 1/20 0.39
CA2 known ✓ P00918 1/20 0.39
ALDH1A1 P00352 4/20 0.49
CYP3A4 P08684 1/20 0.49
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 1/20 0.43
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR2 P34972 6/20 0.41
CNR1 P21554 4/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
BLM P54132 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9181809 0.84 TDP1 (0.44) ALDH1A1KMT2AMEN1HPGDL3MBTL1
SCHEMBL5945169 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2
SCHEMBL30302484 0.81 ALDH1A1 (0.55) ALDH1A1CYP3A4KMT2AMEN1HPGD
SCHEMBL6854169 0.81 ALDH1A1 (0.55) ALDH1A1CYP3A4KMT2AMEN1HPGD
SCHEMBL5499804 0.80 CA12 (0.55) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL11526370 0.79 RAB9A (0.53) ALDH1A1CYP3A4KMT2AMEN1MAPT
SCHEMBL8773481 0.79 ALDH1A1 (0.53) ALDH1A1CYP3A4KMT2AMEN1HPGD
SCHEMBL11523408 0.78 ALDH1A1 (0.47) ALDH1A1CYP3A4KMT2AMEN1MAPT
SCHEMBL7029934 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4KMT2AMEN1MAPT
SCHEMBL7036831 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929600-A Process for separating 3- (diethylamino) sodium benzenesulfonate and sodium chloride 赤峰市恒荣化工有限公司 2022-01-14 CN claimed
CN-113929600-A Process for separating 3- (diethylamino) sodium benzenesulfonate and sodium chloride 赤峰市恒荣化工有限公司 2022-01-14 CN disclosed
CN-113929600-A Process for separating 3- (diethylamino) sodium benzenesulfonate and sodium chloride 赤峰市恒荣化工有限公司 2022-01-14 CN disclosed
CN-113929600-A Process for separating 3- (diethylamino) sodium benzenesulfonate and sodium chloride 赤峰市恒荣化工有限公司 2022-01-14 CN disclosed
US-6746526-B1 HAVING AT LEAST HYDROXY-, AMINO- AND SULPHATO- ARYL SUBSTITUTION AVECIA LIMITED (GB) 2004-06-08 US disclosed
EP-1228149-B1 DISAZO DYESTUFFS FOR INK JET PRINTING AVECIA LTD (GB) 2004-04-14 EP disclosed
EP-1228149-A1 DISAZO DYESTUFFS FOR INK JET PRINTING Avecia Limited (GB) 2002-08-07 EP disclosed
WO-2001030917-A1 DISAZODYESTUFFS FOR INK JET PRINTING AVECIA LIMITED (GB) 2001-05-03 WO disclosed
EP-0477373-B1 METAL CHELATE COMPOUND AND OPTICAL RECORDING MEDIUM COMPRISING THE SAME MITSUBISHI CHEM CORP (JP) 1997-11-05 EP disclosed
EP-0446675-B1 Process for the preparation of sodium 3-diethylaminobenzene-sulfonate BASF AG (DE) 1993-12-08 EP disclosed
EP-0446649-B1 Process for the preparation of sodium 3-diethylaminobenzene-sulfonate BASF AG (DE) 1993-11-10 EP disclosed
US-5231173-A DISAZO METAL CHELATE COMPOUNDS FOR OPTICAL RECORDING MEDIA MITSUBISHI KASEI CORPORATION (JP) 1993-07-27 US disclosed
EP-0477373-A1 METAL CHELATE COMPOUND AND OPTICAL RECORDING MEDIUM COMPRISING THE SAME Mitsubishi Chemical Corporation (JP) 1992-04-01 EP disclosed
EP-0446649-A1 Process for the preparation of sodium 3-diethylaminobenzene-sulfonate BASF Aktiengesellschaft (DE) 1991-09-18 EP disclosed
EP-0446675-A1 Process for the preparation of sodium 3-diethylaminobenzene-sulfonate BASF Aktiengesellschaft (DE) 1991-09-18 EP disclosed