Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034258 | 0.88 | ADORA2B (0.56) | ADORA2BALDH1A1ADORA2AADORA3KDM4E | |
| SCHEMBL7039451 | 0.88 | ADORA2B (0.86) | ADORA2BALDH1A1ADORA2AKDM4EMAPT | |
| SCHEMBL7037369 | 0.86 | ADORA2B (0.88) | ADORA2BALDH1A1ADORA2AADORA3KDM4E | |
| SCHEMBL1946868 | 0.82 | ADORA2B (0.58) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL5411870 | 0.81 | ADORA2B (1.00) | ADORA2BALDH1A1ADORA2AKDM4EMAPT | |
| SCHEMBL7030152 | 0.76 | ADORA2B (0.70) | ADORA2BALDH1A1ADORA2AHPGD | |
| SCHEMBL14344322 | 0.74 | ADORA2B (0.68) | ADORA2BADORA2AADORA3HPGDADORA1 | |
| SCHEMBL1946977 | 0.74 | ADORA2B (0.67) | ADORA2BADORA2AADORA3HPGDADORA1 | |
| SCHEMBL7031251 | 0.74 | ADORA2B (0.71) | ADORA2BADORA2AADORA3BLMHSD17B10 | |
| SCHEMBL10395302 | 0.73 | ADORA2B (0.63) | ADORA2BALDH1A1ADORA2AADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956855-B1 | Immunosuppressive effects of 8 substituted xanthine derivatives | LEUVEN K U RES & DEV (BE) | 2003-03-12 | — | — | EP | claimed |