SCHEMBL7037263

SCHEMBL7037263

COC(=O)C(C)=CC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
NFKB1 P19838 1/20 0.32
MAPT P10636 3/20 0.31
KDM4E B2RXH2 1/20 0.31
TET2 Q6N021 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12065716 1.00 ALDH1A1 (0.43) ALDH1A1KEAP1NFE2L2HCAR2MGAM
SCHEMBL14749991 1.00 ALDH1A1 (0.43) ALDH1A1KEAP1NFE2L2HCAR2MGAM
Acetic Acid SCHEMBL27317270 0.95 ALDH1A1 (0.40) ALDH1A1KEAP1NFE2L2HCAR2MAPT
SCHEMBL28023754 0.83 ALDH1A1 (0.43) ALDH1A1KEAP1NFE2L2HCAR2MGAM
SCHEMBL1821221 0.82
SCHEMBL1821223 0.82
SCHEMBL7771274 0.81 HCAR2 (0.46) ALDH1A1KEAP1NFE2L2HCAR2MGAM
SCHEMBL5953576 0.81 HCAR2 (0.46) ALDH1A1KEAP1NFE2L2HCAR2MGAM
SCHEMBL7771328 0.81 ALDH1A1 (0.42) ALDH1A1KEAP1NFE2L2HCAR2MAPT
SCHEMBL599552 0.81 ALDH1A1 (0.42) ALDH1A1KEAP1NFE2L2HCAR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104178065-B A kind of high-speed coating line peels off the preparation method of transfer adhesive CHANGFENG CHEMICALS INTERNATIONAL LTD. (CN) 2016-03-16 CN disclosed
US-20030032736-A1 Acrylic adhesive compositions containing ketonyl (meth)acrylate KNEAFSEY BRENDAN J (IE) 2003-02-13 US disclosed
WO-2001051576-A1 ACRYLIC ADHESIVE COMPOSITIONS CONTAINING KETONYL (METH)ACRYLATE LOCTITE (R & D) LIMITED (IE) 2001-07-19 WO disclosed