SCHEMBL28023754

SCHEMBL28023754

COC(=O)C(C)=CC(=O)C=C(C)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
NFKB1 P19838 1/20 0.32
TRPA1 O75762 1/20 0.32
MAPT P10636 4/20 0.31
KDM4E B2RXH2 1/20 0.31
TET2 Q6N021 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27622701 0.91 ALDH1A1 (0.37) ALDH1A1MGAMGAASIMGAM2
SCHEMBL5445282 0.85 ALDH1A1 (0.42) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28190969 0.84 ALDH1A1 (0.36) ALDH1A1MGAMGAASIMGAM2
SCHEMBL12065716 0.83 ALDH1A1 (0.43) ALDH1A1MGAMGAASIMGAM2
SCHEMBL7037263 0.83 ALDH1A1 (0.43) ALDH1A1MGAMGAASIMGAM2
SCHEMBL14749991 0.83 ALDH1A1 (0.43) ALDH1A1MGAMGAASIMGAM2
SCHEMBL7771328 0.81 ALDH1A1 (0.42) ALDH1A1KEAP1NFE2L2HCAR2MAPT
SCHEMBL5953576 0.81 HCAR2 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL7771274 0.81 HCAR2 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL774085 0.81 HCAR2 (0.46) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106167479-A A kind of preparation method of Caronic anhydride 南通雅本化学有限公司 2016-11-30 CN claimed
CN-105121410-B Herbicidally active 2- (substituted-phenyl) -cyclopentane-1, 3-dione compounds and derivatives thereof SYNGENTA LTD. (GB) 2019-11-01 CN disclosed
CN-108484491-A A kind of acrylate compounds and application thereof 北京微医智慧信息技术有限责任公司 2018-09-04 CN disclosed
CN-105283446-B Herbicidally active 2- (substituted-phenyl) -cyclopentane-1, 3-dione compounds and derivatives thereof 先正达有限公司 2018-06-12 CN disclosed
CN-104870430-B Herbicidally active cyclic dione compounds substituted by phenyl groups having alkynyl-containing substituents or derivatives thereof 先正达有限公司 2018-05-29 CN disclosed
CN-108003027-A 1-O- caffeoylquinic acids, its derivative, preparation method and its usage 北京微医智慧信息技术有限责任公司 2018-05-08 CN disclosed
CN-107074755-A Herbicides compounds 先正达参股股份有限公司 2017-08-18 CN disclosed
CN-106458958-A Herbicidal propynyl-phenyl compounds 先正达参股股份有限公司 2017-02-22 CN disclosed
CN-103764634-B N-epoxide pyrazolo-three azatropylidenes-derovatives 先正达参股股份有限公司 2016-12-14 CN disclosed
CN-106167479-A A kind of preparation method of Caronic anhydride 南通雅本化学有限公司 2016-11-30 CN disclosed
CN-106167479-A A kind of preparation method of Caronic anhydride 南通雅本化学有限公司 2016-11-30 CN disclosed
CN-103974618-B 2- (substituted phenyl) -cyclopentane-1, 3-dione compounds and derivatives thereof SYNGENTA LTD. (GB) 2016-02-24 CN disclosed
CN-105339347-A Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof SYNGENTA LTD 2016-02-17 CN disclosed
CN-105283446-A Herbicidally active 2- (substituted-phenyl) -cyclopentane-1, 3-dione compounds and derivatives thereof SYNGENTA LTD 2016-01-27 CN disclosed
CN-105263894-A Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof SYNGENTA LTD 2016-01-20 CN disclosed
CN-105121410-A Herbicidally active 2- (substituted-phenyl) -cyclopentane-1, 3-dione compounds and derivatives thereof SYNGENTA LTD 2015-12-02 CN disclosed
CN-104870430-A Herbicidally active cyclic dione compounds substituted by phenyl groups having alkynyl-containing substituents or derivatives thereof SYNGENTA LTD 2015-08-26 CN disclosed