Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 known ✓ | Q02750 | 2/20 | 0.43 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991120 | 0.89 | RAB9A (0.45) | RAB9AMEN1NPC1KMT2AATM | |
| Trifluoromethanesulfonic Acid SCHEMBL5973436 | 0.88 | RAB9A (0.44) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL11332836 | 0.88 | NFE2L2 (0.46) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL27612252 | 0.88 | SMN1; SMN2 (0.53) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL27477118 | 0.88 | NFE2L2 (0.46) | RAB9AMEN1NPC1KMT2AATM | |
| Trifluoromethanesulfonic Acid SCHEMBL8720556 | 0.88 | RAB9A (0.44) | RAB9AMEN1NPC1KMT2AATM | |
| Formaldehyde SCHEMBL17443195 | 0.87 | MEN1 (0.61) | RAB9AMEN1NPC1KMT2AATM | |
| Methyl Alcohol SCHEMBL28009509 | 0.87 | RAB9A (0.61) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL9359592 | 0.87 | MEN1 (0.67) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL29371456 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472753-A2 | PROTON CONDUCTING MEMBRANES FOR HIGH TEMPERATURE FUEL CELLS DEVELOPED WITH SOLD STATE \"WATER FREE\" PROTON CONDUCTING MEMBRANES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-11-03 | — | — | EP | claimed |
| US-20030148162-A1 | Fuel cell is fabricated as a highly conducting sheet of converted solid state organic amine salt, such as converted acid salt of triethylenediamine with two quaternized tertiary nitrogen atoms, combined with a nanoparticulate oxide,a | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-08-07 | — | — | US | claimed |
| WO-2003063266-A2 | PROTON CONDUCTING MEMBRANES FOR HIGH TEMPERATURE FUEL CELLS DEVELOPED WITH SOLD STATE 'WATER FREE' PROTON CONDUCTING MEMBRANES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-07-31 | — | — | WO | claimed |