Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 3/20 | 0.54 |
| ▸ | CCR8 | P51685 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259178 | 0.88 | CCR1 (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29871243 | 0.88 | CCR1 (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| Bromide SCHEMBL16739305 | 0.86 | CCR1 (0.41) | CCR1CCR5CCR8ALDH1A1TRPA1 | |
| SCHEMBL8585585 | 0.81 | KDM4E (0.45) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7972258 | 0.81 | ASIC3 (0.53) | KDM4ENPC1ALDH1A1HSP90AA1PIM1 | |
| SCHEMBL4535559 | 0.81 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29603676 | 0.81 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30485802 | 0.81 | LOXL2 (0.56) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL28416719 | 0.81 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7036361 | 0.81 | LOXL2 (0.56) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055477-A1 | METHOD FOR THE TREATMENT OF MC RECEPTOR RELATED DISORDERS WITH A CHELATE AND/OR A CHELATOR | 7TM PHARMA A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
| WO-2003003009-A1 | USE OF METAL-ION CHELATES IN VALIDATING BIOLOGICAL MOLECULES AS DRUG TARGETS IN TEST ANIMAL MODELS | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003003008-A1 | CHEMICAL LIBRARIES USEFUL FOR DRUG DISCOVERY PROCESSES | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| US-5563273-A | COLOR CHANGE AGENT | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0431547-B1 | Charge transfer salts and uses thereof | IBM (US) | 1994-09-21 | — | — | EP | disclosed |
| US-5179467-A | Color for visual displays in electrochemical cells | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| WO-1991008507-A1 | CHARGE TRANSFER SALTS AND USES THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1991-06-13 | — | — | WO | disclosed |
| EP-0431547-A2 | Charge transfer salts and uses thereof | International Business Machines Corporation (US) | 1991-06-12 | — | — | EP | disclosed |