Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871243 | 0.83 | CCR1 (0.42) | LOXL2ALDH1A1TRPA1TSHRPDCD1 | |
| SCHEMBL1259178 | 0.83 | CCR1 (0.42) | LOXL2ALDH1A1TRPA1TSHRPDCD1 | |
| SCHEMBL2956020 | 0.81 | LOXL2 (0.43) | LOXL2ALDH1A1HTR1ACYP11B1CYP11B2 | |
| Bromide SCHEMBL16739305 | 0.81 | CCR1 (0.41) | LOXL2ALDH1A1TRPA1TSHR | |
| SCHEMBL7037544 | 0.81 | KDM4E (0.54) | ALDH1A1TRPA1TSHRHSP90AA1PIM1 | |
| SCHEMBL5991845 | 0.81 | LOXL2 (0.70) | ASIC3LOXL2HTR1AHTR7AURKA | |
| SCHEMBL995901 | 0.81 | ASIC3 (0.53) | ASIC3LOXL2HTR1AHTR7TSHR | |
| SCHEMBL4116786 | 0.81 | ASIC3 (0.53) | ASIC3LOXL2ALDH1A1HTR1AHTR7 | |
| SCHEMBL10434579 | 0.81 | ASIC3 (0.53) | ASIC3LOXL2HTR1AHTR7FFAR1 | |
| SCHEMBL10271516 | 0.81 | ASIC3 (0.53) | ASIC3LOXL2ALDH1A1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165038-A | Cyclic metal ruthenium nitrosyl complex, preparation method and application as NO release photosensitizer | 中南民族大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118165038-A | Cyclic metal ruthenium nitrosyl complex, preparation method and application as NO release photosensitizer | 中南民族大学 | 2024-06-11 | — | — | CN | disclosed |
| EP-3750890-A1 | ALKOXYBENZO-FIVE-MEMBERED (SIX-MEMBERED) HETEROCYCLIC AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Fudan University (CN) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154047-A1 | ALKOXYBENZO-FIVE-MEMBERED (SIX-MEMBERED) HETEROCYCLIC AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | 复旦大学 | 2019-08-15 | — | — | WO | disclosed |
| US-6281359-B1 | PSYCHOLOGICAL DISORDERS | NEUROGEN CORPORATION | 2001-08-28 | — | — | US | disclosed |
| US-6221871-B1 | TREATING SCHIZOPHRENIA, DEPRESSION OR PARKINSON'S DISEASE | NEUROGEN CORPORATION | 2001-04-24 | — | — | US | disclosed |
| US-5912350-A | Certain aminomethyl biphenyl, aminomethyl phenyl pyridine and aminomethyl phenyl pyrimidine derivatives; novel dopamine receptor subtype selective ligands | NEUROGEN CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| US-5677454-A | DIAGNOSIS, THERAPY OF SCHIZOPHRENIA, DEPRESSION, PARKINSONISM | NEUROGEN CORPORATION (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0793662-A1 | AMINOMETHYL ARYL COMPOUNDS; DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | NEUROGEN CORPORATION (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5594141-A | ANTIPSYCHOTIC AND ANTIDEPRESSANT AGENTS; PARKINSON'S DISEASE | NEUROGEN CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996016058-A1 | AMINOMETHYL ARYL COMPOUNDS; DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | NEUROGEN CORPORATION (US) | 1996-05-30 | — | — | WO | disclosed |