Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781169 | 0.76 | MEN1 (0.55) | CRHBPCRHR2MEN1KMT2ALMNA | |
| SCHEMBL7929465 | 0.76 | CRHBP (0.42) | CRHBPCRHR2MEN1KMT2ALMNA | |
| SCHEMBL11648613 | 0.74 | CRHBP (0.57) | CRHBPCRHR2MEN1KMT2AFASN | |
| SCHEMBL13346222 | 0.74 | MAPT (0.59) | CRHBPCRHR2MEN1KMT2ALMNA | |
| SCHEMBL17378980 | 0.71 | MEN1 (0.50) | CRHBPCRHR2MEN1KMT2ALMNA | |
| SCHEMBL2281450 | 0.71 | CRHBP (0.53) | CRHBPCRHR2MEN1KMT2AHTT | |
| SCHEMBL5707253 | 0.71 | CRHBP (1.00) | CRHBPCRHR2MEN1KMT2APOLB | |
| SCHEMBL5958789 | 0.71 | HSP90AA1 (0.59) | CRHBPCRHR2MEN1KMT2ALMNA | |
| SCHEMBL27682423 | 0.71 | TDP1 (0.52) | CRHBPCRHR2MEN1KMT2ALMNA | |
| SCHEMBL22658133 | 0.70 | MEN1 (0.62) | CRHBPCRHR2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |