Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410940 | 0.79 | TTR (0.48) | TTRHTTMEN1KMT2ALMNA | |
| SCHEMBL7038673 | 0.76 | CRHBP (0.54) | CRHBPCRHR2HTTMEN1KMT2A | |
| SCHEMBL28556066 | 0.76 | PDE4B (0.42) | CRHBPCRHR2PDE4BPDE4APDE4C | |
| SCHEMBL7929549 | 0.73 | CRHBP (0.54) | CRHBPCRHR2BACE1HDAC4HDAC2 | |
| SCHEMBL9254935 | 0.72 | BACE1 (0.44) | CRHBPCRHR2PDE4BPDE4APDE4C | |
| SCHEMBL69776 | 0.71 | TTR (0.56) | TTRHTTMEN1KMT2ALMNA | |
| SCHEMBL7932602 | 0.70 | TTR (0.43) | CRHBPCRHR2PTPN1TTRHTT | |
| SCHEMBL598477 | 0.69 | ALDH1A1 (0.50) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL1754108 | 0.69 | PDE4B (0.52) | CRHBPCRHR2PDE4BPDE4APDE4C | |
| SCHEMBL29001722 | 0.69 | PDE4B (0.58) | CRHBPCRHR2PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| EP-0707849-A1 | USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S.L. (ES) | 1996-04-24 | — | — | EP | disclosed |