SCHEMBL7038878

SCHEMBL7038878

CC(C)OC(=O)N[C@@H](CNC(=O)c1ccc(OCCNc2ncccn2)cc1O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 6/20 0.38
ITGAV P06756 5/20 0.38
EGLN2 Q96KS0 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
ITGB1 P05556 3/20 0.37
ITGA5 P08648 3/20 0.37
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
PGGT1B P53609 1/20 0.36
ITGA2B P08514 2/20 0.36
EGLN1 Q9GZT9 1/20 0.36
MAOB P27338 3/20 0.35
PPARD Q03181 1/20 0.35
CASR P41180 1/20 0.35
KLKB1 P03952 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036629 0.92 EGLN2 (0.39) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7030553 0.90 ITGB3 (0.46) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7032427 0.90 ITGB3 (0.41) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7038923 0.89 ITGB3 (0.40) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7039296 0.89 ITGB1 (0.41) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7035965 0.88 MEN1 (0.44) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7038444 0.88 ITGB3 (0.39) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7032608 0.88 ITGB3 (0.42) ITGB3ITGAVEGLN2ITGB1ITGA5
SCHEMBL7035435 0.87 ITGB3 (0.40) ITGB3ITGAVEGLN2MEN1KMT2A
SCHEMBL7032362 0.87 CASP1 (0.41) ITGB3ITGAVEGLN2ITGB1ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR ITGB3 403/4885ITGAV 289/4885EGLN2 2165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.