Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986410 | 0.85 | SIRT6 (0.66) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL25796990 | 0.83 | SIRT6 (0.63) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL22489080 | 0.81 | MEN1 (0.64) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL6824323 | 0.81 | SIRT6 (0.56) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL25279405 | 0.80 | POLB (0.59) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL22175056 | 0.79 | SIRT6 (0.63) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL25200165 | 0.77 | MAPT (0.59) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL17373705 | 0.77 | MAPT (0.59) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL15271381 | 0.77 | SIRT6 (0.81) | SIRT6MAPTALDH1A1POLBADRB1 | |
| SCHEMBL6151230 | 0.77 | SIRT6 (0.81) | SIRT6MAPTALDH1A1POLBADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
| EP-1185236-A2 | COMPOSITIONS FOR DYEING KERATINIC FIBRES, CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH AN AZETIDINYL GROUP | L'OREAL (FR) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001041724-A2 | COMPOSITIONS FOR DYEING KERATINIC FIBRES, CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH AN AZETIDINYL GROUP | L'OREAL (FR) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | KRT18, CDC73, AOC1 | SIRT6 3772/4885MAPT 1146/4885ALDH1A1 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.