Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986410 | 0.84 | SIRT6 (0.66) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL25447124 | 0.81 | SIRT6 (0.58) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL5727087 | 0.81 | SIRT6 (0.62) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL7039030 | 0.81 | SIRT6 (0.57) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL25279405 | 0.79 | POLB (0.59) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL22175056 | 0.78 | SIRT6 (0.63) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL6822186 | 0.76 | RAB9A (0.45) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL25200165 | 0.76 | MAPT (0.59) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL17373705 | 0.76 | MAPT (0.59) | SIRT6ADRB1MAPTALDH1A1POLB | |
| SCHEMBL15271381 | 0.75 | SIRT6 (0.81) | SIRT6ADRB1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |