Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038187 | 0.91 | CHEK2 (0.62) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7042112 | 0.86 | RHEB (0.58) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL3200579 | 0.86 | CHEK2 (0.69) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7036871 | 0.86 | KDM4E (0.48) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7038591 | 0.83 | CHEK2 (0.56) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7035502 | 0.83 | KDM4E (0.71) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7034855 | 0.82 | CHEK2 (0.54) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7041702 | 0.79 | MMP2 (0.54) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL11563729 | 0.78 | CHEK2 (0.78) | CHEK2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL3918744 | 0.77 | CHEK2 (0.80) | CHEK2KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030104473-A1 | Common ligand mimics: benzimidazoles | TRIAD THERAPEUTICS, INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030104473-A1 | Common ligand mimics: benzimidazoles | BID, LIFR, FGFR3 | CHEK2 2711/4885KMT2A 2386/4885KDM4E 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.