Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 9/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | MPL | P40238 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036871 | 0.91 | KDM4E (0.48) | MMP2MMP9MMP8MMP13HDAC6 | |
| SCHEMBL7943528 | 0.86 | MMP2 (0.71) | MMP2MMP9MMP8MMP13CHEK2 | |
| SCHEMBL7038187 | 0.86 | CHEK2 (0.62) | MMP2MMP9MMP8MMP13HDAC6 | |
| SCHEMBL7037076 | 0.85 | CHEK2 (0.65) | MMP2MMP9MMP8MMP13HDAC6 | |
| SCHEMBL7035502 | 0.83 | KDM4E (0.71) | MMP2MMP9MMP8MMP13HDAC6 | |
| SCHEMBL7040027 | 0.82 | CHEK2 (0.62) | MMP2MMP9MMP8MMP13CHEK2 | |
| SCHEMBL7039869 | 0.79 | CHEK2 (0.53) | MMP2MMP9MMP8MMP13HDAC6 | |
| SCHEMBL11564587 | 0.78 | CHEK2 (0.78) | MMP2MMP9MMP8MMP13CHEK2 | |
| SCHEMBL7034621 | 0.78 | SMN1; SMN2 (0.54) | MMP2MMP9MMP8MMP13HDAC6 | |
| SCHEMBL7038591 | 0.78 | CHEK2 (0.56) | HDAC6CHEK2NR4A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030104473-A1 | Common ligand mimics: benzimidazoles | TRIAD THERAPEUTICS, INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030104473-A1 | Common ligand mimics: benzimidazoles | BID, LIFR, FGFR3 | MMP2 3735/4885MMP9 4396/4885MMP8 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.