SCHEMBL7040045

SCHEMBL7040045

CCC(C)Nc1ccc(C=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.69
HSD17B10 Q99714 3/20 0.69
CYP3A4 P08684 2/20 0.69
ALOX15 P16050 2/20 0.69
TSHR P16473 2/20 0.69
HIF1A Q16665 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
TP53 P04637 1/20 0.69
HSP90AA1 P07900 1/20 0.69
THRB P10828 1/20 0.69
CASP1 P29466 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
TYR P14679 1/20 0.45
ALDH1A3 P47895 3/20 0.42
ALDH3A1 P30838 2/20 0.42
CYP2A6 P11509 3/20 0.40
ALOX12 P18054 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49805 0.83 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL8646926 0.81 ADH1B (0.46) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL7707476 0.80 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL11560859 0.80 ADH1B (0.49) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL11281185 0.80 ADH1B (0.49) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL4901085 0.79 TYR (0.52) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL21688334 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL48404 0.78 ALDH1A1 (0.78) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL10725182 0.78 TAAR1 (0.56) ALDH1A1HSD17B10CYP3A4ALOX15TSHR
SCHEMBL9874686 0.77 ALDH1A1 (0.86) ALDH1A1HSD17B10CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030096379-A1 Method for producing tryptamine derivatives BIOCATALYTICS, INC. 2003-05-22 US disclosed
WO-2002079153-A1 METHOD FOR PRODUCING TRYPTAMINE DERIVATIVES BIOCATALYTICS, INC. (US) 2002-10-10 WO disclosed
US-H2046-H1 AUTOMATED ALTERNATING SOLUTION DEPOSITION OF POLYCATIONIC AND POLYANIONIC LAYERS; ULTRASMOOTH ELECTROOPTIC FILMS THAT DO NOT REQUIRE ELECTRIC FIELD POLING OR HIGH TEMPERATURE TREATMENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECERETARY OF THE NAVY 2002-09-03 US disclosed