Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040045 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL8646926 | 0.80 | ADH1B (0.46) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL11560859 | 0.79 | ADH1B (0.49) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL11281185 | 0.79 | ADH1B (0.49) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL9725343 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL9513873 | 0.76 | TYR (0.34) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL4901085 | 0.75 | TYR (0.52) | ALDH1A1HSD17B10L3MBTL1CYP3A4ALOX15 | |
| SCHEMBL7251917 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HSD17B10L3MBTL1CYP3A4TSHR | |
| SCHEMBL10725182 | 0.73 | TAAR1 (0.56) | ALDH1A1HSD17B10CYP3A4ALOX15TSHR | |
| SCHEMBL21507504 | 0.72 | TYR (0.48) | ALDH1A1HSD17B10TYRALDH1A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-0412101-B1 | NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM | EASTMAN KODAK CO (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5086161-A | Ultraviolet radiation screening food packaging | EASTMAN KODAK COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5075491-A | Ultraviolet radiation absorbers | EASTMAN KODAK COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-5068348-A | For food packaging | EASTMAN KODAK COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0412101-A1 | NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM. | EASTMAN KODAK CO (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4958043-A | Novel methine compounds, polymers containing them and formed articles therefrom | EASTMAN KODAK COMPANY (US) | 1990-09-18 | — | — | US | disclosed |