Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686339 | 0.89 | PPARG (0.36) | PPARGRXRAAGBL2MAPTTDP1 | |
| SCHEMBL11663434 | 0.82 | LMNA (0.37) | PPARGFFAR4TDP1MAPK1PTGDR2 | |
| SCHEMBL1387817 | 0.81 | PPARG (0.49) | PPARGRXRAMAPTTDP1CYP1A2 | |
| SCHEMBL9142278 | 0.79 | AKR1B1 (0.45) | PPARGPMP22LMNATSHRHPGD | |
| SCHEMBL31288115 | 0.78 | PPARG (0.49) | PPARGRXRAMAPTTDP1CYP1A2 | |
| SCHEMBL11663913 | 0.77 | METAP1 (0.42) | PPARGMAPTCYP1A2PTGS2PTGDR2 | |
| SCHEMBL11662018 | 0.77 | PTGS2 (0.34) | PPARGRXRAPTGS2ALDH1A1ABCB11 | |
| SCHEMBL11662750 | 0.75 | ABCB11 (0.38) | PPARGFFAR1PTGS2PTGDR2KDM4E | |
| SCHEMBL20409091 | 0.75 | HSD17B10 (0.41) | MAPTTDP1KDM4ETSHRHSD17B10 | |
| SCHEMBL11663761 | 0.75 | PPARG (0.38) | PPARGFFAR1TDP1PTGDR2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003003012-A1 | IDENTIFICATION OF INTERACTING MOLECULES | MEDIMOLECULAR PTY. LTD. (AU) | 2003-01-09 | — | — | WO | disclosed |