Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 14/20 | 0.57 |
| ▸ | NPC1 | O15118 | 13/20 | 0.57 |
| ▸ | RAB9A | P51151 | 13/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108604 | 0.81 | NPC1 (0.69) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3128277 | 0.80 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3125413 | 0.78 | NPC1 (0.75) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28559369 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL18010003 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL12435043 | 0.73 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8788256 | 0.73 | MAPT (0.70) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787875 | 0.73 | MAOB (0.55) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2242715 | 0.73 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL5226589 | 0.73 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6221343-B1 | Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2001-04-24 | — | — | US | disclosed |
| EP-1028120-A1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | L'OREAL (FR) | 2000-08-16 | — | — | EP | disclosed |