Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.69 |
| ▸ | RAB9A | P51151 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | PKM | P14618 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170729 | 0.92 | ALDH1A1 (0.57) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL3125413 | 0.90 | NPC1 (0.75) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL4496832 | 0.87 | NPC1 (0.57) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL2324292 | 0.86 | NPC1 (0.78) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL4496843 | 0.85 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL4813791 | 0.83 | NPC1 (0.58) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL2242715 | 0.82 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL31429762 | 0.82 | GAA (0.66) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL15643913 | 0.82 | SMN1; SMN2 (0.64) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL29269112 | 0.82 | AMY1A (0.71) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0843995-A2 | Use of substituted benzazoles as UV absorbents, new benzazoles and their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |