Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.60 |
| ▸ | RAB9A | P51151 | 14/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17969360 | 0.84 | ESR1 (0.50) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18794913 | 0.82 | RAB9A (0.52) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24557010 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7040174 | 0.80 | SMN1; SMN2 (0.57) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL824375 | 0.79 | NPC1 (0.69) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29531707 | 0.79 | NPC1 (0.69) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13700935 | 0.79 | ELANE (0.61) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17969362 | 0.78 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11159396 | 0.78 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17969427 | 0.77 | NPC1 (0.50) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | claimed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | claimed |
| EP-1353642-B1 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AMPHIPHILIC COPOYLMER COMPRISING 2-ACRYLAMIDO-2-PROPANESULFONIC AND (METH)ACRYLATES | OREAL (FR) | 2008-05-07 | — | — | EP | claimed |
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | claimed |
| US-7045120-B2 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | L'OREAL (FR) | 2006-05-16 | — | — | US | claimed |
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | claimed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | claimed |
| EP-1370232-A2 | COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES | L'OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| EP-1353642-A1 | AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS WITH AT LEAST ONE MONOMER HAVING ETHYLENIC UNSATURATION WITH A SULPHONIC GROUP AND COMPRISING A HYDROPHOBIC PART | L'OREAL (FR) | 2003-10-22 | — | — | EP | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| EP-1317918-A1 | Cosmetic sunscreen compositions based on synergistic filter mixture and their use | L'OREAL (FR) | 2003-06-11 | — | — | EP | claimed |
| WO-2002056858-A1 | SOLAR PROTECTION COMPOSITIONS | L'OREAL (FR) | 2002-07-25 | — | — | WO | claimed |
| WO-2002055045-A1 | AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS WITH AT LEAST ONE MONOMER HAVING ETHYLENIC UNSATURATION WITH A SULPHONIC GROUP AND COMPRISING A HYDROPHOBIC PART | L'OREAL (FR) | 2002-07-18 | — | — | WO | claimed |
| WO-2002049597-A2 | COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES | L'OREAL (FR) | 2002-06-27 | — | — | WO | claimed |
| WO-2002039972-A1 | INSOLUBLE ORGANIC UV FILTERS AND COSMETIC USE THEREOF | L'OREAL (FR) | 2002-05-23 | — | — | WO | claimed |
| JP-10158248-A | — | — | None | — | — | JP | disclosed |
| CN-1149091-A | Storage-stable liquid brightener formulations | HOECHST AG (DE) | 1997-05-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | CUTA, DSG1, PCNA | NPC1 3176/4885RAB9A 4654/4885ALDH1A1 2367/4885 |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SUCLG1, CUTA, DLD | NPC1 2529/4885RAB9A 4067/4885ALDH1A1 246/4885 |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | NPC1 3790/4885RAB9A 3821/4885ALDH1A1 28/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | NPC1 3007/4885RAB9A 4526/4885ALDH1A1 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.