Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160762 | 0.82 | HTT (0.58) | HTTALDH1A1CYP2A6CA1CA2 | |
| SCHEMBL13004058 | 0.78 | AOC3 (0.44) | HTTALDH1A1CYP2A6CA1CA2 | |
| SCHEMBL7043934 | 0.77 | PTGS2 (0.51) | ALDH1A1GAAMAPK1L3MBTL1TSHR | |
| SCHEMBL1908685 | 0.74 | CA1 (0.52) | ALDH1A1GAACA1CA2CA12 | |
| SCHEMBL9320735 | 0.73 | SLC1A3 (0.42) | HTTCA1CA2TSHRKMT2A | |
| SCHEMBL4775938 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CYP2A6CA1CA2CA12 | |
| SCHEMBL6422240 | 0.72 | AOC3 (0.53) | ALDH1A1GAACA1CA2CA12 | |
| SCHEMBL4480601 | 0.72 | HDAC3 (0.41) | HTTALDH1A1GAAPOLB | |
| SCHEMBL7042356 | 0.72 | ESR1 (0.41) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL1731978 | 0.72 | CNR1 (0.44) | CYP2A6MAPK1TDP1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4365162-A2 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | Intervet International B.V. (NL) | 2024-05-08 | — | — | EP | disclosed |
| US-20240051943-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INC. (US) | 2024-02-15 | — | — | US | disclosed |
| EP-4263528-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | Intervet International B.V. (NL) | 2023-10-25 | — | — | EP | disclosed |
| CN-116635370-A | Process for preparing N- (bis (4-methoxyphenyl) methyl) -6-oxo-2- (pyridazin-3-yl) -1, 6-dihydropyrimidine-5-carboxamide | 英特维特国际股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| EP-4219588-A1 | POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY | Mitsubishi Gas Chemical Company, Inc. (JP) | 2023-08-02 | — | — | EP | disclosed |
| EP-3750939-B1 | POLYCARBONATE RESIN, PRODUCTION METHOD THEREFOR, AND OPTICAL MOLDED BODY | MITSUBISHI GAS CHEMICAL CO (JP) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022136206-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022136206-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-30 | — | — | WO | disclosed |
| EP-0659737-B1 | Catecholamine surrogates useful as beta 3 agonists | BRISTOL MYERS SQUIBB CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-5776983-A | ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0659737-A2 | Catecholamine surrogates useful as B3 agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051943-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | DPYD, TPMT, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | HTT 1281/4885ALDH1A1 696/4885CYP2A6 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.